Vasopressin decreases neuronal apoptosis during cardiopulmonary resuscitation

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Vasopressin combined with epinephrine decreases cerebral perfusion compared with vasopressin alone during cardiopulmonary resuscitation in pigs.

BACKGROUND AND PURPOSE It is unknown whether a combination of vasopressin and epinephrine may be superior to vasopressin alone by targeting both nonadrenergic and adrenergic receptors. METHODS After 15 minutes of cardiac arrest (13 minutes of ventricular fibrillation and 2 minutes of pulseless electrical activity) and 3 minutes of chest compressions, 16 animals were randomly treated with eith...

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Capnography during cardiopulmonary resuscitation.

Use of waveform capnography during cardiac arrest was recomended in the 2010 International Consensus on Cardiopulmonary esuscitation (CPR) Science with Treatment Recommendations.1 primary benefit includes confirmation that a tracheal tube (or ther airway device) has been placed correctly and is providing entilation of the lungs.2 Capnography is considerably more relible than either clinical ass...

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Vasopressin and epinephrine vs. epinephrine alone in cardiopulmonary resuscitation.

BACKGROUND During the administration of advanced cardiac life support for resuscitation from cardiac arrest, a combination of vasopressin and epinephrine may be more effective than epinephrine or vasopressin alone, but evidence is insufficient to make clinical recommendations. METHODS In a multicenter study, we randomly assigned adults with out-of-hospital cardiac arrest to receive successive...

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Re: Neural injury after use of vasopressin and adrenaline during porcine cardiopulmonary resuscitation

Dear Editor, Halvorsen and colleagues (1) investigated cerebral and cardiac tissue injury subsequent to use of vasopressin and adrenaline in combination compared with vasopressin alone during cardiopulmonary resuscitation (CPR). They concluded that combined use of vasopressin and adrenaline caused greater signs of cerebral and cardiac injury than use of vasopressin alone during experimental CPR...

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Neural injury after use of vasopressin and adrenaline during porcine cardiopulmonary resuscitation

BACKGROUND Our aim was to investigate cerebral and cardiac tissue injury subsequent to use of vasopressin and adrenaline in combination compared with vasopressin alone during cardiopulmonary resuscitation (CPR). METHODS In a randomized, prospective, laboratory animal study 28 anesthetized piglets were subject to a 12-min untreated cardiac arrest and subsequent CPR. After 1 min of CPR, 10 of t...

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ژورنال

عنوان ژورنال: Neural Regeneration Research

سال: 2014

ISSN: 1673-5374

DOI: 10.4103/1673-5374.130107